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  • The expression and clinical significance of the miRNA-200 family in gastric cancer

    Abstract  Gastric cancer is one of the most common malignant tumors and one of the leading causes of cancer‑related mortality. Recent studies have revealed t...查看详情>>

  • The downregulation of miR-200c/141 promotes ZEB1/2 expression and gastric cancer progression

    Abstract  Gastric cancer is the fourth most common malignancy in the world. Although microRNA-200 (miR-200) family members are thought to play roles in tumori...查看详情>>

  • A functional polymorphism rs11614913 in microRNA-196a2 is associated with an increased risk of colorectal cancer although not with tumor stage and grade. Biomed Rep

    Author Wang N, Li Y, Zhu LJ, Zhou RM, Jin W, Guo XQ, Wang CM, Chen ZF, Liu WAbstract  A C/T polymorphism (rs11614913) was identified in the microRNA (miRNA) 19...查看详情>>

  • Hsa-miR-196a2 functional SNP is associated with the risk of ESCC in individuals under 60 years old

    Author Wang N, Li Y, Zhou RM, Wang GY, Wang CM, Chen ZF, Liu WAbstract  Background and aim: The miR-196a2 gene contains a C/T polymorphism (rs11614913). Its...查看详情>>

  • Expression and mechanism of PinX1 and telomerase activity in the carcinogenesis of esophageal epithelial cells

    Author Zuo J, Wang DH, Zhang YJ, Liu L,Liu FL,Liu WAbstract  Esophageal tissues were collected from an esophageal carcinoma high-risk area of China and were...查看详情>>

  • miRNA-200c increases the sensitivity of breast cancer cells to doxorubicin through the suppression of E-cadherin-mediated PTEN/Akt signaling. Molecular medicine reports

    Author Chen Y,Sun Y,Chen L,Xu X,Zhang X,Wang B,Min L,Liu WAbstract  Doxorubicin (ADR) is successfully used to treat breast cancer, however, it is often assoc...查看详情>>

  • Effect of topotecan on retinocytoma cell apoptosis and expression of Livin and PTEN

    BACKGROUND:Retinocytoma (RB) is a very common intraocular malignant tumor during infancy. Chemotherapy has gradually been used as the first-line treatment for intraocular RB in recent years. In this study, Livin and PTEN expressions were observed in the R...查看详情>>

  • Combination of ginsenoside Rg3 with chemotherapy enhances the inhibitory effects of esophageal squamous cell carcinoma in mice. Molecular and Clinical Oncology

    The present study was conducted in order to investigate the inhibitory effects of ginsenoside Rg3 combined with chemotherapy on Eca-109 esophageal squamous cell carcinoma (ESCC) in mice. Tumor xenograft models were established in the right forelimb of 20...查看详情>>

  • microRNA-200c regulates the sensitivity of chemotherapy of gastric cancer SGC7901/DDP cells by directly targeting RhoE. Pathol Oncol Res

    Gastric cancer remains a worldwide burden as the second leading cause of cancer-related death. Drug resistance of chemotherapy looms as a major clinical obstacle to successful treatment. Recent evidence indicated that miRNA-200c can restore the sensitivit...查看详情>>

  • The inhibitory effects of Endostar combined with chemotherapy on human Esophageal squamous cell carcinoma xenograft in mice. Molecular Biology Reports

      The purpose of this study was to investigate the efficacy of Endostar combined with chemotherapy on human esophageal squamous cell carcinoma Eca-109 in mice...查看详情>>

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